Product Identification

Product Name

1-Methyl-1H-imidazole

Synonyms

1H-Imidazole, 1-methyl-
1-Methyl-1H-imidazole
N-Methylimidazole

CAS

616-47-7

Formula

C4H6N2

Molecular Weight

82.11

EINECS

210-484-7

RTECS

NI7000000

RTECS Class

Other

Beilstein/Gmelin

3685968

Beilstein Reference

4-04-00-02368

EC Index Number

613-035-00-7

EC Class

Harmful; Corrosive

Physical and Chemical Properties

Appearance

Colorless to light yellow liquid with an amine-like odor.

Solubility in water

Very soluble

Melting Point

-2

Boiling Point

198

Vapor Pressure

.3

Density

1.030 g/cm3 (20 C)

pKa/pKb

6.99 (pKb)

Heat Of Vaporization

54.64 kJ/mol

Heat Of Combustion

-2505 kJ/mol

Usage

Use as a solvent, a base, a catalyst, a mimic for purine nucleoside bases and histidine and histamine.

Vapor Density

2.83

Refractive Index

1.4970 (20 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.

Eyes

Get medical aid. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Discard contaminated shoes. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Effects may be delayed. Causes chemical burns to the respiratory tract. The toxicological properties of this substance have not been fully investigated. Aspiration may lead to pulmonary edema. May cause systemic effects. Inhalation at high concentrations may cause CNS depression and asphixiation.

Skin

Causes skin burns. Effects may be delayed. May cause cyanosis of the extremities. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.

Eyes

Causes eye burns. May cause chemical conjunctivitis and corneal damage.

Ingestion

May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May cause systemic effects.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 21/22 34

EC Safety Phrase

S 26 36 45

UN (DOT)

3267

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Effects may be delayed.

Poison Class

4

Fire Fighting Measures

Flash Point

92

Autoignition

525

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. May polymerize explosively when involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Extinguishing media: Use water spray to cool fire-exposed containers. Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray.

Upper exp. limit

15.7

Lower exp. limit

2.7

Fire Potential

Combustible material: may burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Stability and Reactivity

Disposal Code

1

Incompatibilities

Acid anhydrides, acid chlorides, acids, carbon dioxide, moisture, strong oxidizing agents.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

3267

Hazard Class

8

Packing Group

I; II; III

HS Code

2933 29 90