Product Identification

Product Name

Tetracaine hydrochloride

Synonyms

2-(Dimethylamino)ethyl 4-butylaminobenzoate monohydrochloride
2-(Dimethylamino)ethyl p-(butylamino)benzoate hydrochloride
4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester
Pantocaine hydrochloride

CAS

136-47-0

Formula

C15H25ClN2O2

Molecular Weight

300.83

EINECS

205-248-5

RTECS

DG4900000

RTECS Class

Drug; Mutagen; Primary Irritant

Merck

12,9330

Beilstein/Gmelin

3918400

Beilstein Reference

4-14-00-01172

Physical and Chemical Properties

Melting Point

148 - 148

pKa/pKb

8.39(at 25℃) (pKa)

Usage

Topical opththalmic anesthetic; used for spinal anesthesia.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Inhalation

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. Readily absorbed through skin. May be harmful if absorbed through the skin.

Eyes

Causes eye irritation.

Ingestion

Toxic if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

25 36 43

EC Safety Phrase

26 36/37 45

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Toxic. Toxic if swallowed. Irritating to eyes. May cause sensitization by skin contact. Readily absorbed through skin. Target organ(s): Nerves.

Fire Fighting Measures

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities

Iodides, inorganic mercury, silver salts.

Stability

Stable at normal temperatures and pressures.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2811

Hazard Class

6.1

Packing Group

III