Product Identification

Product Name

Sulbactam

Synonyms

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, (2S,5R)-
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, (2S-cis)-
Betamaze
Penicillanic acid 1,1-dioxide
Penicillanic acid S,S-dioxide
Penicillanic acid sulfone

CAS

68373-14-8

Formula

C8H11NO5S

Molecular Weight

233.25

EINECS

269-878-2

Merck

12,9058

Physical and Chemical Properties

Melting Point

170

Boiling Point

356

Partition Coefficient

-1.04

Usage

Is given in combination with beta-lactam antibiotics to inhibit beta-lactamase, an enzyme produced by bacteria that destroys the antibiotics. Sulbactam is an irreversible inhibitor of beta-lactamase; it binds the enzyme and does not allow it to interact with the antibiotic. .