Product Identification

Product Name

6,7-Dihydroxycoumarin

Synonyms

6,7-Dihydroxy-2H-1-benzopyran-2-one
6,7-Dihydroxycoumarin
Aesculetin
Cichorigenin
Cichoriin aglycon
Esculetol

CAS

305-01-1

Formula

C9H6O4

Molecular Weight

178.14

EINECS

206-161-5

RTECS

GN6382500

RTECS Class

Drug; Natural Product

Merck

13,3731

Beilstein/Gmelin

152788

Beilstein Reference

5-18-03-00202

Physical and Chemical Properties

Appearance

Yellow crystalline powder.

Solubility in water

Soluble

Melting Point

267

Boiling Point

470

Vapor Pressure

2E-9 (25 C)

pKa/pKb

8.63 (pKa)

Partition Coefficient

.55

Heat Of Vaporization

76.0 kJ/mol

Usage

Substance is used in filters for absorption of ultraviolet light.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. The toxicological properties of this substance have not been fully investigated.

Skin

No information regarding skin irritation and other potential effects was found.

Eyes

No information regarding eye irritation and other potential effects was found.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 36/37/38

EC Safety Phrase

S 26 36

UN (DOT)

1759

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Flash Point

201

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1759

Hazard Class

8

Packing Group

I; II; III