Product Identification

Product Name

2-Desoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose

Synonyms

1-Methyl-1-nitroso-3-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea
D-Glucose, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-

CAS

18883-66-4

Formula

C8H15N3O7

Molecular Weight

265.22000000000003

EINECS

242-646-8

RTECS

LZ5775000

RTECS Class

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data

Merck

12,8991

Beilstein/Gmelin

2060674

Physical and Chemical Properties

Appearance

Off-white powder.

Solubility in water

Soluble

Melting Point

184

pKa/pKb

9.36 (pKa)

Usage

Antibiotic.

First Aid Measures

Ingestion

DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.

Inhalation

IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.

Skin

IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

Eyes

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage

Store at unopened vials in the refrigerator. Once reconstituted with 5% dextrose or saline in sterile water, the solution may be kept 24 hours under refrigeration.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Irritating substances may induce pulmonary edema or pneumonitis. Embolization of insolouble material may occur.

Skin

Avoid any skin contact. See Inhalation.

Eyes

See Inhalation.

UN (DOT)

3249

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate protective gloves, clothing and goggles.

Respirators

Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).

Exposure Effects

The toxological properties of this substance have not been fully investigated.

Exposure limit(s)

OSHA: Possible Select carcinogen.

Fire Fighting Measures

Fire Fighting

Use method most appropriate to fight surrounding fire.

Fire Potential

Non-Combustible

Accidental Release Measures

Small spills/leaks

Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.

Stability and Reactivity

Stability

No data.

Incompatibilities

Reacts exothermically with acids Reacts with both strong oxidizing agents and strong reducing agents.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

3249

Hazard Class

6.1

Packing Group

II; III