Product Identification

Product Name

4-Methylpentanoic acid

Synonyms

Isobutylacetic acid
4,4-Dimethylbutanoic acid
4-Methylpentanoic acid
4-Methylvaleric acid
Isohexanoic acid
Isohexoic acid

CAS

646-07-1

Formula

C6H12O2

Molecular Weight

116.16

EINECS

211-464-0

RTECS

NR2975000

RTECS Class

Primary Irritant

Beilstein/Gmelin

1741912

Beilstein Reference

4-02-00-00944

EC Class

harmful, corrosive

Physical and Chemical Properties

Appearance

Colorless liquid.

Solubility in water

Slightly soluble

Melting Point

-35

Boiling Point

200

Vapor Pressure

0.13 (25 C)

Density

0.9192 g/cm3 (20 C)

pKa/pKb

4.78 (pKa)

Partition Coefficient

1.66

Heat Of Vaporization

48.2 kJ/mol

Heat Of Combustion

-3506 kJ/mol

Usage

Used as an intermediate in the manufacture of plasticizers, pharmaceuticals, and perfumes; occurs naturally in many edible plants and dairy products.

Saturation Concentration

Very low

Vapor Density

4

Refractive Index

1.4124 (25 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do not use mouth-to-mouth respiration if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30 minutes).

Handling and Storage

Storage

Keep away from sources of ignition. Store in a tightly closed container. Corrosives area. Store in a cool, dry area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Use only in a chemical fume hood. Discard contaminated shoes.

Hazards Identification

Inhalation

Causes chemical burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Aspiration may lead to pulmonary edema. May cause systemic effects.

Skin

Harmful if absorbed through the skin. Causes skin burns. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.

Eyes

Causes eye burns. May cause chemical conjunctivitis and corneal damage.

Ingestion

May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause perforation of the digestive tract. May cause systemic effects.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 21 34

EC Safety Phrase

S 26 36/37/39 45

UN (DOT)

1760

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Effects may be delayed.

Fire Fighting Measures

Flash Point

89

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: This material is lighter than water and insoluble in water. The fire could easily be spread by the use of water in an area where the water cannot be contained. In case of fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Provide ventilation.

Stability and Reactivity

Disposal Code

4

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, strong bases.

Decomposition

Carbon monoxide, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1760

Hazard Class

8

Packing Group

I; II; III

HS Code

2915 90 80