Product Identification

Product Name

2-Hydroxybenzoic acid

Synonyms

2-Hydroxybenzoic acid
o-Caroxyphenol
o-Hydroxybenzoic acid

CAS

69-72-7

Formula

C7H6O3

Molecular Weight

138.12

EINECS

200-712-3

RTECS

VO0525000

RTECS Class

Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant

Merck

12,8484

Beilstein/Gmelin

774890

Beilstein Reference

4-10-00-00125

EC Class

harmful, irritant

Physical and Chemical Properties

Appearance

White crystals, usually in fine needles, or fluffy crystalline powder. Odorless and has a sweetish, followed by acrid taste.

Solubility in water

Very soluble

Boiling Point

336

Vapor Pressure

.000045

Density

1.443 g/cm3

pKa/pKb

2.97 (pKa)

Partition Coefficient

2.26

Heat Of Vaporization

61.2 kJ/mol

Heat Of Combustion

-588 kJ/mol

Usage

Manufacture of aspirin and salicylates, resins, dyestuff intermediate, prevulcanisation inhibitor, analytical reagent, fungicide.

Vapor Density

4.8

Refractive Index

1.5204

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid. Induce vomiting by giving one teaspoon of Syrup of Ipecac.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from sources of ignition. Do not store in direct sunlight. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

Causes irritation of the mucous membrane and upper respiratory tract.

Skin

Contact with skin causes irritation and possible burns, especially if the skin is wet or moist. If absorbed, may cause symptoms similar to those for ingestion. May cause skin rash and eruptions.

Eyes

Causes severe eye irritation. May result in corneal injury.

Ingestion

Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause salicylism; characterized by headache, dizziness, ringing in the ears, hearing difficulty, visual disturbances, mental confusion, drowsiness, sweating thirst, hyperventilation, nausea, vomiting and diarrhea. May be harmful if swallowed. Severe salicylate intoxication may cause central nervous system disturbances such as convulsions and coma, skin eruptions, and alteration in the acid-base balance.

Hazards

Dusts at sufficient concentrations can form explosive mixtures in air.

EC Risk Phrase

R 22 36/37/38

EC Safety Phrase

S 26 36/37/39

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

May cause reproductive and fetal effects. Laboratory experiments have resulted in mutagenic effects. May cause salicylism with effects similar to those of skin absorption. May cause damage to the kidneys and pancrease.

Poison Class

3

Fire Fighting Measures

Flash Point

145

Autoignition

500

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Water or foam may cause frothing. Use agent most appropriate to extinguish fire.

Upper exp. limit

8.6

Lower exp. limit

1.5

Fire Potential

Slightly. Requires preheating. Slight hazard.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Incompatibilities

Oxidizing agents, lead acetate, iron salts, alkalis, iodine, spirit nitrous ether.

Stability

Stable under normal temperatures and pressures. Moisture sensitive. Light sensitive. Darkens on exposure to light.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Irritating vapors of unburned material and phenol may form in fire.

Transport Information

HS Code

2918 21 00