Product Identification

Product Name

N-Desmethylpefloxacin

Synonyms

1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
AM-715
Baccidal
MK-366

CAS

70458-96-7

Formula

C16H18FN3O3

Molecular Weight

319.33999999999997

EINECS

274-614-4

RTECS

VB2005000

RTECS Class

Drug; Mutagen; Reproductive Effector; Human Data

Merck

12,6793

Beilstein/Gmelin

567897

Beilstein Reference

5-23-03-00135

Physical and Chemical Properties

Solubility in water

Soluble

Melting Point

227 - 228

Boiling Point

556

Vapor Pressure

3E-13 (25 C)

pKa/pKb

2.75 (pKa)

Heat Of Vaporization

88.1 kJ/mol

Usage

Antibiotic. Inhibits the activity of a bacterial enzyme (gyrase) that is necessary for proper dna formation and replication.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed. Store at 2-8 C

Hazards Identification

Inhalation

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. May be harmful if absorbed through the skin.

Eyes

May cause eye irritation.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Safety Phrase

22 24/25

Exposure Controls/Personal Protection

Personal Protection

Exercise appropriate precautions to minimize direct contact with skin or eyes and prevent inhalation of dust.

Respirators

Wear dust mask.

Exposure Effects

Avoid contact and inhalation.

Fire Fighting Measures

Flash Point

290

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen fluoride.