Product Identification

Product Name

2-Amino-1,3-propanediol

Synonyms

1,3-Dihydroxy-2-propylamine
1,3-Dihydroxyisopropylamine
2-Amino-1,3-dihydroxypropane
2-Amino-1,3-propanediol
2-Aminoglycerol
Serinol

CAS

534-03-2

Formula

C3H9NO2

Molecular Weight

91.1

EINECS

208-584-0

Beilstein/Gmelin

635683

Beilstein Reference

3-04-00-00846

Physical and Chemical Properties

Appearance

White to light yellow crystals.

Solubility in water

Very soluble

Melting Point

91 - 95

Boiling Point

267

Vapor Pressure

0.0012 (25 C)

pKa/pKb

5.45 (pKb)

Partition Coefficient

-1.51

Heat Of Vaporization

58.6 kJ/mol

Refractive Index

1.4891 (20 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Storage under a nitrogen blanket has been recommended. Store protected from moisture.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

Inhalation

The toxicological properties of this substance have not been fully investigated. Inhalation of dust may cause respiratory tract irritation.

Skin

May cause skin irritation and possible burns. The toxicological properties of this material have not been fully investigated.

Eyes

Dust may cause mechanical irritation. May cause eye irritation and possible burns. The toxicological properties of this material have not been fully investigated.

EC Risk Phrase

R 34

EC Safety Phrase

S 26 36/37/39 45

UN (DOT)

3259

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Flash Point

115

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Carbon monoxide, oxides of nitrogen, carbon dioxide.

Transport Information

UN Number

3259