Product Identification

Product Name

2,3,3-Trichloro-2-propene-1-thiol diisopropylcarbamate

Synonyms

S-(2,3,3-Trichloro-2-propenyl) bis(1-methylethyl)carbamothioate
S-(2,3,3-Trichloroallyl) diisopropylthiocarbamate
S-(2,3,3-Trichloroprop-2-enyl) (di(propan-2-yl)amino)methanethioate

CAS

2303-17-5

Formula

C10H16Cl3NOS

Molecular Weight

304.67

EINECS

218-962-7

RTECS

EZ8575000

RTECS Class

Agricultural Chemical and Pesticide; Mutagen

Merck

12,9726

Beilstein/Gmelin

1875853

EC Index Number

006-039-00-X

EC Class

Harmful; Sensitising; Dangerous for the Environment

Physical and Chemical Properties

Appearance

Colorless crystals or oily amber liquid.

Solubility in water

Insoluble

Melting Point

29-30

Boiling Point

322

Vapor Pressure

0.0003 (25 C)

Density

1.273 g/cm3 (25 C)

Partition Coefficient

4.6

Heat Of Vaporization

56.4 kJ/mol

Usage

Herbicide.

First Aid Measures

Ingestion

Ipecac induced vomiting is not recommended because of the potential for cns depression and seizures. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Intravenous fluids may be useful in restoring extracellular fluid volume following severe vomiting and diarrhea. Oxygen therapy is effective in relieving the distress of antabuse-like reactions rarely associated with exposure to thiram and possibly the mbdt-carb compounds. No specific antidotes are available for poisoning by these compounds. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.

Inhalation

Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.

Skin

Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.

Eyes

Immediately flush with running water for at least 20 minutes.

Handling and Storage

Storage

Store in well-ventilated area, above freezing.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Respiratory failure, requiring ventilatory support, has been reported following ingestions.

Skin

Exposure to dusts, sprays, solutions, wettable powder suspensions or emulsions of these agents may lead to skin and mucous membrane irritation.

Eyes

See Inhalation.

Ingestion

Nausea, vomiting and diarrhea may occur.

UN (DOT)

2757

Exposure Controls/Personal Protection

Personal Protection

Wear rubber gloves and goggles when handling.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Exposure Effects

Exposure to thiram or mbdt-carb (based on animal studies) may cause weakness, ataxia, ascending paralysis and hypothermia. Peripheral neuropathy (pain, numbness and weakness of the extremities) has been noted following exposure to thiuram (the ethyl analog of thiram). No adverse reproductive effects (testicular parameters) in male mice were observed following methyl thiophanate doses up to 1000 mg/kg orally for 5 consecutive days (Traina et al, 1998). Maternal toxicity was evident in female rats.

Poison Class

4

Fire Fighting Measures

Flash Point

95

Fire Fighting

Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Use alcohol foam, dry chemical or carbon dioxide.

Fire Potential

Non-Combustible

Accidental Release Measures

Small spills/leaks

Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water. Water spill: Use natural barriers or oil spill control booms to limit spill travel. Use natural deep water pockets, excavated lagoons, or sand bag barriers to trap material at bottom. Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.

Stability and Reactivity

Incompatibilities

Incompatible with strong acids and bases, and especially

Stability

Indefinitely stable, insensitive to light or heat stable under normal storage conditions. Hydrolyzed by strong acids and alkalis.

Decomposition

When heated to decomposition it emits very toxic fumes of hydrogen chloride, nitrogen oxides and sulfur oxides.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2757

Hazard Class

6.1

Packing Group

I; II; III