Product Identification

Product Name

Manganese(II) ethane-1,2-diylbis(dithiocarbamate)

Synonyms

[[1,2-Ethanediylbis[carbomodithioato]]-(2-)] manganese
Ethylenebis(dithiocarbamato)manganese
Ethylenebis[dithiocarbamic acid], manganous salt
Farmaneb
Maneb preparation, with not less than 60% Maneb
Rhodianebe

CAS

12427-38-2

Formula

C4H6MnN2S4

Molecular Weight

265.3

EINECS

235-654-8

RTECS

OP0700000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector

Beilstein/Gmelin

811388 (G)

EC Index Number

006-077-00-7

EC Class

Irritant; Sensitising

Physical and Chemical Properties

Appearance

Maneb (or) maneb preparations is a yellow to brown colored crystalline solid.

Solubility in water

moderately soluble

Vapor Pressure

8E-8 (25 C)

Density

1.92 g/cm3 (20 C)

Usage

Fungicide for vegetables, for seed treatment of vegetables & field crops, for deciduous fruits & nuts.

First Aid Measures

Ingestion

Ipecac induced vomiting is not recommended because of the potential for cns depression and seizures. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Intravenous fluids may be useful in restoring extracellular fluid volume following severe vomiting and diarrhea. Oxygen therapy is effective in relieving the distress of antabuse-like reactions rarely associated with exposure to thiram and possibly the mbdt-carb compounds. No specific antidotes are available for poisoning by these compounds. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.

Ingestion

Nausea, vomiting and diarrhea may occur.

Inhalation

Respiratory failure, requiring ventilatory support, has been reported following ingestions.

Inhalation

Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.

Skin

Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.

Skin

Exposure to dusts, sprays, solutions, wettable powder suspensions or emulsions of these agents may lead to skin and mucous membrane irritation.

Eyes

In case of contact with substance, immediately flush with running water for at least 20 minutes.

Eyes

See Skin.

Handling and Storage

Storage

Keep in well-ventilated area. Keep away from fire and sparks. Do not allow wetting or overheating, which could cause deterioration of fungicidal effectiveness and may generate flammable vapors.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Respiratory failure, requiring ventilatory support, has been reported following ingestions.

Skin

Exposure to dusts, sprays, solutions, wettable powder suspensions or emulsions of these agents may lead to skin and mucous membrane irritation.

Eyes

See Skin.

Ingestion

Nausea, vomiting and diarrhea may occur.

Hazards

May ignite on contact with moist air or moisture. May burn rapidly with flare-burning effect. Some react vigorously or explosively on contact with water. Some may decompose explosively when heated or involved in a fire. May re-ignite after fire is extinguished. Runoff may create fire or explosion hazard.

UN (DOT)

2210

UN (DOT)

2968

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate chemical protective clothing.

Respirators

Wear positive pressure self-contained breathing apparatus.

Exposure Effects

Exposure to thiram or mbdt-carb (based on animal studies) may cause weakness, ataxia, ascending paralysis and hypothermia. Peripheral neuropathy (pain, numbness and weakness of the extremities) has been noted following exposure to thiuram (the ethyl analog of thiram). No adverse reproductive effects (testicular parameters) in male mice were observed following methyl thiophanate doses up to 1000 mg/kg orally for 5 consecutive days (Traina et al, 1998). Maternal toxicity was evident in female rats.

Exposure limit(s)

TLV (as Mn): ppm; 5 mg/m3 (as TWA) (ACGIH 1994-1995).

Poison Class

4

Fire Fighting Measures

Fire Fighting

Do not extinguish fire unless flow can be stopped. Do not use water. Use graphite, soda ash, powdered sodium chloride, or suitable dry powder.

Fire Potential

Flammable/combustible material.

Accidental Release Measures

Small spills/leaks

Do not use water. Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Keep material dry.

Stability and Reactivity

Stability

May spontaneously decompose vigorously when stored in bulk. Also decomposes at about 100 C.

Decomposition

Decomposes without melting at 192-204 C. Decomposes on prolonged exposure to air or moisture. When heated to decomposition it emits highly toxic fumes of oxides of nitrogen and sulfoxides.

Combustion Products

Fire will produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2210

UN Number

2968

Hazard Class

4.2

Hazard Class

4.3

Packing Group

III