Product Identification

Product Name

4-Methylthiazole-5-carboxylic acid

Synonyms

4-Methyl-1,3-thiazole-5-carboxylic acid

CAS

20485-41-0

Formula

C5H5NO2S

Molecular Weight

143.16999999999999

RTECS

XJ3680000

Beilstein/Gmelin

120745

Beilstein Reference

4-27-00-04008

Physical and Chemical Properties

Solubility in water

14 g/L (25 C)

Melting Point

235 - 241

Boiling Point

304

Vapor Pressure

0.0004 (25 C)

Density

1.42 g/cm3 (25 C)

pKa/pKb

0.94 (pKa)

Partition Coefficient

.58

Heat Of Vaporization

57.43 kJ/mol

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep container tightly closed.

Hazards Identification

Ingestion

May be harmful if swallowed.

Inhalation

Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.

Skin

May cause skin irritation. May be harmful if absorbed through the skin. May cause allergic skin reaction.

Eyes

May cause irritation.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

43

EC Safety Phrase

37/39

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.

Respirators

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator.

Fire Fighting Measures

Flash Point

137

Fire Fighting

Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable at normal temperratures and pressures.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.