Product Identification

Product Name

Honokiol

Synonyms

[1,1'-Biphenyl]-2,4'-diol, 3',5-di-2-propenyl-
3',5-Diallyl-2,4'-biphenyldiol

CAS

35354-74-6

Formula

C18H18O2

Molecular Weight

266.33999999999997

Merck

12,4780

Physical and Chemical Properties

Appearance

White solid. A biphenolic compound present in the cones, bark, and leaves of Magnolia grandifloris that has been used in the traditional Japanese medicine

Solubility in water

Insoluble

Melting Point

86 - 86.5

Boiling Point

400

Density

1.107 g/cm3 (20 C)

pKa/pKb

9.63

Partition Coefficient

4.2

Heat Of Vaporization

67.7 kJ/mol

Usage

An anxiolytic, anti-thrombotic, anti-depressant, anti-emetic, and anti-bacterial.

Handling and Storage

Storage

Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 4 C.

Hazards Identification

Inhalation

If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.

Skin

In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.

Eyes

Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention.

Ingestion

Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.

Exposure Controls/Personal Protection

Personal Protection

Lab coat, impervious gloves, safety glasses.

Fire Fighting Measures

Flash Point

184

Fire Fighting

Extinguish with dry chemical powder, water spray, foam or fog. Do not use water jet. Fire fighters should wear positive pressure self-contained breathing apparatus (SCBA) and full turnout gear.

Fire Potential

May be combustible at high temperatures.

Accidental Release Measures

Small spills/leaks

Use shovel to put the material into a convenient waste disposal container.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.