Product Identification

Product Name

1-Phenylpiperazine

Synonyms

N-Phenylpiperazine
NPP

CAS

92-54-6

Formula

C10H14N2

Molecular Weight

162.24

EINECS

202-165-6

RTECS

TM2625000

RTECS Class

Mutagen; Primary Irritant

Beilstein/Gmelin

132157

Beilstein Reference

5-23-01-00160

EC Class

toxic, corrosive

Physical and Chemical Properties

Appearance

Clear colorless to light yellow liquid.

Solubility in water

Very soluble

Melting Point

17 - 19

Boiling Point

286

Density

1.0725 g/cm3 (14 C)

pKa/pKb

5.06 (pKb)

Refractive Index

1.5844 (16.8 C)

First Aid Measures

Ingestion

Do NOT induce vomiting. Allow the victim to rinse his mouth and then to drink 2-4 cupfuls of water, and seek medical advice.

Inhalation

Remove from exposure to fresh air immediately.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Handling and Storage

Storage

Keep containers tightly closed. Store in a cool, dry area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use only in a chemical fume hood. Discard contaminated shoes.

Hazards Identification

Ingestion

Harmful if swallowed. Causes gastrointestinal tract irritation.

Inhalation

Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema. Inhalation may produce burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting. Causes irritation of the mucous membrane and upper respiratory tract.

Skin

May be fatal if absorbed through the skin. Causes severe skin irritation and possible burns. Substance is readily absorbed through the skin.

Eyes

Causes severe eye irritation and possible burns. May cause chemical conjunctivitis and corneal damage.

EC Risk Phrase

R 22 24 34

EC Safety Phrase

S 26 28 36/37/39 45

UN (DOT)

2927

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Poison Class

3

Fire Fighting Measures

Flash Point

140

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.

Stability and Reactivity

Disposal Code

9

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Transport Information

UN Number

2927

HS Code

2933 59 95