Product Identification

Product Name

2,4-Diamino-5-(3,4-dimethoxybenzyl)pyrimidine

Synonyms

2,4-Diamino-5-(3,4-dimethoxybenzyl)pyrimidine
2,4-Diamino-5-veratrylpyrimidine
5-((3,4-Dimethoxyphenyl)methyl)-2,4-pyrimidinediamine
EGIS-5645

CAS

5355-16-8

Formula

C13H16N4O2

Molecular Weight

260.3

EINECS

226-333-3

RTECS

UV8142000

RTECS Class

Drug; Mutagen

Merck

12,3041

Beilstein/Gmelin

258464

Beilstein Reference

5-25-13-00391

Physical and Chemical Properties

Appearance

White solid

Solubility in water

Insoluble

Melting Point

232 - 236

Boiling Point

506

Vapor Pressure

2E-10 (25 C)

pKa/pKb

6.59 (pKb)

Heat Of Vaporization

77.6 kJ/mol

Usage

Antibiotic, antiprotozoal.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Handling and Storage

Storage

Keep tightly closed. Store at 2-8 C

Hazards Identification

Inhalation

Material is irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.

Skin

Causes skin irritation. May be harmful if absorbed through the skin.

Eyes

Causes eye irritation.

Ingestion

May be harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

36/37/38

EC Safety Phrase

26 36

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Irritant. Irritating to eyes, respiratory system and skin.

Fire Fighting Measures

Flash Point

260

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides.