Product Identification

Product Name

6-O-Methylerythromycin

Synonyms

(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-(4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl)oxy-14-ethyl-12,13-dihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl)oxy-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
6-O-Methylerythromycin A
Antibiotic TE 31
Clathromycin
Klaricid
Zeclar

CAS

81103-11-9

Formula

C38H69NO13

Molecular Weight

747.96

EINECS

433-820-6

RTECS

KF4997000

Merck

12,2400

Physical and Chemical Properties

Appearance

White solid.

Solubility in water

Insoluble

Melting Point

217

Density

1.18 g/cm3 (20 C)

pKa/pKb

5.84 (pKb)

Partition Coefficient

3.16

Usage

A macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia.

First Aid Measures

Ingestion

Vomiting may be induced if person is conscious. Obtain medical attention.

Inhalation

Remove to fresh air. Restore and/or support breathing as needed. Obtain Medical attention.

Skin

Wash contaminated area twice with soap and water. Obtain medical attention.

Eyes

Flush with running water for 15 minutes holding eyelids open. Obtain medical attention.

Handling and Storage

Storage

Store only in original container. Keep container tightly closed.

Fire Fighting Measures

Fire Fighting

Use media suitable for fire in surrounding area. Wear full protective clothing and self-contained breathing apparatus.

Accidental Release Measures

Small spills/leaks

Sweep up and transfer to container for disposal.

Exposure Controls/Personal Protection

Exposure Effects

The potential for exposure is reduced in finished pharmaceutical form. The signs of overexposure are nausea, vomiting, diarrhea and abdominal pain.