Product Identification

Product Name

EGCG

Synonyms

(-)-Epigallocatechin-3-o-gallate
(-)-Epigallocatechol gallate
[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 3,4,5-trihydroxybenzoate
Epigallocatechin 3-gallate
Tea catechin

CAS

989-51-5

Formula

C22H18O11

Molecular Weight

458.38

RTECS

KB5200000

Merck

12,3568

Physical and Chemical Properties

Appearance

Solid. The most abundant catechin in tea.

Solubility in water

Slightly soluble

Melting Point

140 - 142

Density

1.90 g/cm3 (20 C)

pKa/pKb

7.75 (pKa)

Partition Coefficient

2.08

Usage

An antioxidant that helps protect the skin from uv radiation-induced damage and tumor formation.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed. Store at 2-8 C.

Hazards Identification

Ingestion

May be harmful if swallowed.

Inhalation

Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.

Skin

May cause irritation. May be harmful if absorbed through the skin.

Eyes

May cause irritation.

Exposure Controls/Personal Protection

Personal Protection

Chemical safety goggles, protective gloves.

Respirators

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks.

Fire Fighting Measures

Fire Fighting

Extinguish with water spray, carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Combustion Products

Emits toxic fumes under fire conditions.