Product Identification

Product Name

4-Fluorobenzenesulfonyl chloride

Synonyms

4-Fluorophenylsulfonyl chloride
p-Fluorobenzenesulfonyl chloride
p-Fluorophenylsulfonyl chloride

CAS

349-88-2

Formula

C6H4ClFO2S

Molecular Weight

194.6

EINECS

206-493-0

Beilstein/Gmelin

2091633

Beilstein Reference

4-11-00-00102

Physical and Chemical Properties

Appearance

White solid.

Solubility in water

Insoluble

Melting Point

36

Boiling Point

263

Vapor Pressure

0.02 (25 C)

Partition Coefficient

2.3

Heat Of Vaporization

48.1 kJ/mol

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation and possible burns. The toxicological properties of this material have not been fully investigated.

Eyes

May cause eye irritation and possible burns. The toxicological properties of this material have not been fully investigated.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 34

EC Safety Phrase

S 26 36/37/39 45

UN (DOT)

1759

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Flash Point

113

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Do NOT use water directly on fire. Use foam, dry chemical, or carbon dioxide. Use agent most appropriate to extinguish fire.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Provide ventilation.

Stability and Reactivity

Incompatibilities

Bases, amines.

Stability

Stable under normal temperatures and pressures.

Decomposition

Hydrogen chloride, carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1759

Hazard Class

8

Packing Group

I; II; III