Product Identification

Product Name

Indole-3-acetone

Synonyms

2-Propanone, 1-(1H-indol-3-yl)
3-(2-Oxopropyl)indole
3-Acetonylindole
3-Indolylacetone
Indol-3-yl-2-propanone
Indole-3-acetone

CAS

1201-26-9

Formula

C11H11NO

Molecular Weight

173.21

EINECS

214-855-4

Merck

13,4989

Physical and Chemical Properties

Appearance

Tan solid.

Solubility in water

1.2 g/L

Melting Point

118 - 119

Boiling Point

342

Vapor Pressure

7.9E-5 (25 C)

Density

1.167 g/cm3 (20 C)

pKa/pKb

16.67 (pKa)

Partition Coefficient

1.36

Heat Of Vaporization

58.53 kJ/mol

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Store at 2 - 8 C.

Hazards Identification

Skin

May cause irritation.

Eyes

May cause irritation.

Hazards

Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.

Respirators

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks.

Exposure Effects

May be harmful by inhalation, ingestion, or skin absorption.

Fire Fighting Measures

Flash Point

168

Fire Fighting

Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Oxides of carbon and nitrogen.