(1R,2S)-(-)-Ephedrine(299-42-3)
Product Identification
Product Name
(1R,2S)-(-)-Ephedrine
Synonyms
(1R,2S)-2-Methylamino-1-phenylpropan-1-ol
Biophedrin
Eciphin
Efedrin
Ephedral
Sanedrine
CAS
299-42-3
Formula
C10H15NO
Molecular Weight
165.26
EINECS
206-080-5
RTECS
KB0700000
RTECS Class
Drug; Reproductive Effector; Human Data; Natural Product
Beilstein/Gmelin
972533
EC Index Number
614-023-00-4
EC Class
Harmful
First Aid Measures
Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Handling and Storage
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C). Store protected from moisture. Store protected from light.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light.
Exposure Controls/Personal Protection
Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
Elevated blood pressure may occur, accompanied by rapid heart rate may occur. Low heart rate has been reported following overdoses of phenylpropanolamine and as a late presentation following norepinephrine depletion. Increased temperature may occur. anxiety, nervousness, insomnia, muscle tremor, seizures, altered mental status and cerebral hemorrhage and ischemia may be noted. Toxic psychosis may develop following acute overdoses or abuse of sympathomimetics.
Fire Fighting Measures
Flash Point
85
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.