Product Identification

Product Name

1-Methoxy-2-propanol

Synonyms

1-Methoxy-2-hydroxypropane
1-Methoxy-propane-2-ol
Closol
Methoxyisopropanol
Methyl proxitol
Propylene glycol, monomethyl ether

CAS

107-98-2

Formula

C4H10O2

Molecular Weight

90.12

EINECS

203-539-1

RTECS

UB7700000

RTECS Class

Reproductive Effector; Human Data; Primary Irritant

Beilstein/Gmelin

1731270

Beilstein Reference

3-01-00-02146

EC Index Number

603-064-00-3

EC Class

Flammable

Physical and Chemical Properties

Appearance

Clear colorless liquid with ether-like odor, lachrymator, hygroscopic.

Solubility in water

Miscible

Melting Point

-97

Boiling Point

119.6

Vapor Pressure

12

Density

0.9335 g/cm3 (15 C)

Heat Of Vaporization

32.6 kJ/mol

Heat Of Combustion

-2324 kJ/mol

Usage

Chiefly used in manufacture of lacquers & paints.

Vapor Density

> 1

Saturation Concentration

About 1.5% (15000 ppm) at 25 C (calculated)

Refractive Index

1.4034 (20 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Keep containers tightly closed.

Handling

Wash thoroughly after handling. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. Vapors may cause dizziness or suffocation.

Skin

May cause skin irritation. Prolonged and/or frequent contact may cause drying, cracking or folliculitis.

Eyes

May cause eye irritation.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.

Hazards

Flashback along vapor trail may occur. Vapor may explode if ignited in an enclosed area.

EC Risk Phrase

R 10

EC Safety Phrase

S 24

UN (DOT)

3092

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.

Exposure Effects

Repeated or prolonged exposure may cause CNS stimulation.

Exposure limit(s)

TLV: 100 ppm; 369 mg/m3 (as TWA); 150 ppm; 553 mg/m3 (STEL) (ACGIH 1997). MAK: 100 ppm; 375 mg/m3; (1996) NIOSH REL: TWA 100 ppm (360 mg/m3) ST 150 ppm (540 mg/m3)

Poison Class

-

Fire Fighting Measures

Flash Point

31

Autoignition

287

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Use agent most appropriate to extinguish fire. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out.

Upper exp. limit

13.8

Lower exp. limit

1.6

Fire Potential

FLAMMABLE.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. A vapor suppressing foam may be used to reduce vapors.

Stability and Reactivity

Disposal Code

1

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

3092

Hazard Class

3

Packing Group

III

HS Code

2909 49 19