Product Identification

Product Name

Ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(meta-nitrophenyl)-3,5-pyridinedicarboxylate

Synonyms

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester
Bayotensin
Baypress
Ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
Nidrel

CAS

39562-70-4

Formula

C18H20N2O6

Molecular Weight

360.37

EINECS

254-513-1

RTECS

US5653000

RTECS Class

Drug; Reproductive Effector

Merck

12,6669

Beilstein/Gmelin

498823

Beilstein Reference

6-22

Physical and Chemical Properties

Appearance

Yellow to green powder.

Solubility in water

Insoluble

Melting Point

155 - 158

Boiling Point

489

Vapor Pressure

1E-9 (25 C)

pKa/pKb

9.97 (pKa)

Heat Of Vaporization

75.5 kJ/mol

Usage

Ca channel blocker; anti-hypertensive.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Inhalation

Harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. Harmful if absorbed through skin.

Eyes

May cause eye irritation.

Ingestion

Harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

20/21/22

EC Safety Phrase

36

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Harmful by inhalation, in contact with skin and if swallowed.

Fire Fighting Measures

Flash Point

250

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Thermal decomposition may produce carbon monoxide, carbon dioxide, and nitrogen oxides.