Product Identification

Product Name

1,8-Dihydroxy-3-carboxyanthraquinone

Synonyms

1,8-Dihydroxyanthraquinone-3-carboxylic acid
9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid
Cassic acid
Chrysazin-3-carboxylic acid
Monorhein
Rhubarb yellow

CAS

478-43-3

Formula

C15H8O6

Molecular Weight

284.22000000000003

EINECS

207-521-4

RTECS

CA9516000

RTECS Class

Drug

Merck

12,8342

Beilstein/Gmelin

2222155

Beilstein Reference

4-10-00-04088

Physical and Chemical Properties

Appearance

Yellow needles (from methanol) or yellow-brown powder.

Solubility in water

Soluble

Vapor Pressure

4E-15 (25 C)

pKa/pKb

3.17 (pKa)

Partition Coefficient

4.52

Usage

Used in the treatment of skin diseases.

First Aid Measures

Ingestion

Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container.

Handling

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Ingestion

May cause irritation of the digestive tract. May be harmful if swallowed.

Inhalation

Causes respiratory tract irritation. May be harmful if inhaled.

Skin

Causes skin irritation. May be harmful if absorbed through the skin.

Eyes

Causes eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Fire Potential

This material is probably combustible.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability

No data.

Incompatibilities

Strong oxidizing agents, strong bases.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.