Product Identification

Product Name

2,3,4-Trifluorobenzenamine

Synonyms

2,3,4-Trifluoroaniline
Aniline, 2,3,4-trifluoro-

CAS

3862-73-5

Formula

C6H4F3N

Molecular Weight

147.1

EINECS

407-170-9

RTECS

CY1211500

RTECS Class

Primary Irritant

Beilstein/Gmelin

3245609

Beilstein Reference

4-12-00-01114

EC Class

harmful, irritant

Physical and Chemical Properties

Appearance

Brown liquid.

Solubility in water

Slightly soluble

Melting Point

14-15

Boiling Point

174

Vapor Pressure

1.3 (25 C)

Density

1.39 g/cm3

pKa/pKb

11.75 (pKb)

Partition Coefficient

1.68

Heat Of Vaporization

41.0 kJ/mol

Vapor Density

5.07

Refractive Index

1.49 (20 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry place. Store in a tightly closed container.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Aspiration may lead to pulmonary edema. Inhalation at high concentrations may cause CNS depression and asphixiation. Causes irritation of the mucous membrane and upper respiratory tract.

Skin

Causes moderate skin irritation. May cause cyanosis of the extremities.

Eyes

Causes moderate eye irritation. May cause chemical conjunctivitis and corneal damage.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May form methemoglobin which in sufficient concentration causes cyanosis.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 20/21/22 36/38

EC Safety Phrase

S 26 36/37/39

UN (DOT)

2810

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Absorption into the body leads to the formation of methemoglobin which in sufficient concentrations causes cyanosis.

Fire Fighting Measures

Flash Point

68

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible Liquid. Extinguishing media: Use water spray to cool fire-exposed containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Combustible material: may burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Cover with sand, dry lime or soda ash and place in a closed container for disposal. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, strong acids, acid chlorides, acid anhydrides.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide, fluoride fumes, hydrogen fluoride.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2810

Hazard Class

6.1

Packing Group

I; II; III

HS Code

2921 42 10