Product Identification

Product Name

2-Hydroxy-3,5-diiodobenzoic acid

Synonyms

2-Hydroxy-3,5-diiodobenzenecarboxylic acid
2-Hydroxy-3,5-diiodobenzoic acid
3,5-Diiodo-2-hydroxybenzoic acid

CAS

133-91-5

Formula

C7H4I2O3

Molecular Weight

389.91

EINECS

205-124-0

RTECS

VO2800000

RTECS Class

Agricultural Chemical and Pesticide; Drug

Merck

13,3212

Beilstein/Gmelin

2615358

Beilstein Reference

4-10-00-00226

EC Class

irritant

Physical and Chemical Properties

Appearance

White to cream powder.

Solubility in water

Insoluble

Boiling Point

381

Vapor Pressure

2E-6 (25 C)

pKa/pKb

2.07 (pKa)

Partition Coefficient

4.56

Heat Of Vaporization

66.4 kJ/mol

Heat Of Combustion

-2930 kJ/mol

Usage

Used as an iodine source in foods.

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Get medical aid if irritation or symptoms occur.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation.

Skin

Causes skin irritation.

Eyes

Causes eye irritation.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed. Chronic ingestion of iodides during pregnancy has resulted in fetal death, severe goiter, and cretinoid appearance of the newborn.

EC Risk Phrase

R 22 36/37/38

EC Safety Phrase

S 26 36/37/39

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Chronic ingestion of iodides during pregnancy has resulted in fetal death, severe goiter and cretinoid appearance of the newborn..

Fire Fighting Measures

Flash Point

184

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents - strong bases.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen iodide.

Transport Information

UN Number

2811

HS Code

2918 29 90