Product Identification

Product Name

N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide

Synonyms

2-Oxo-1-pyrrolidinylacetic acid,-2,6-dimethylanilide
DM-9384
DMPPA
N-(2,6-Dimethylphenyl)-2-oxo-1-pyrrolidineacetamide
Nefiracetam
Translon

CAS

77191-36-7

Formula

C14H18N2O2

Molecular Weight

246.31

RTECS

UX9655650

Merck

12,6528

Beilstein/Gmelin

6848330

Physical and Chemical Properties

Appearance

White solid.

Solubility in water

0.39 g/L (25 C)

Melting Point

153

Boiling Point

459

Vapor Pressure

1.4E-8 (25 C)

Density

1.19 g/cm3 (20 C)

pKa/pKb

12.24 (pKb)

Partition Coefficient

1.53

Heat Of Vaporization

71.88 kJ/mol

Usage

A nootropic drug of the racetam family.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep container tightly closed.

Hazards Identification

Ingestion

Harmful if swallowed.

Inhalation

Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.

Skin

May cause irritation. May be harmful if absorbed through the skin.

Eyes

May cause irritation.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

22

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.

Respirators

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator.

Fire Fighting Measures

Flash Point

231

Fire Fighting

Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, carbon dioxide, and nitrogen oxides.