Product Identification

Product Name

Ethyl 4-chloro-3-oxobutanoate

Synonyms

4-Chloro-3-oxobutanoic acid ethyl ester
Butanoic acid, 4-chloro-3-oxo-, ethyl ester
Ethyl (chloroacetyl)acetate
Ethyl 4-chloro-3-oxobutanoate
Ethyl 4-chloro-3-oxobutyrate
Ethyl g-chloroacetoacetate

CAS

638-07-3

Formula

C6H9ClO3

Molecular Weight

164.59

EINECS

211-317-0

RTECS

AK5110000

RTECS Class

Other

Beilstein/Gmelin

1761275

Beilstein Reference

4-03-00-01550

EC Class

toxic, corrosive, sensitizing, dangerous for the environment

Physical and Chemical Properties

Appearance

Clear colorless to pale yellow red liquid. Acetic odor.

Solubility in water

Slightly soluble

Melting Point

-8

Boiling Point

236

Vapor Pressure

0.05 (25 C)

Density

1.21 g/cm3

pKa/pKb

9.56 (pKa)

Partition Coefficient

1.67

Heat Of Vaporization

47.2 kJ/mol

Vapor Density

5.68

Refractive Index

1.4221 (19 C)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Do NOT allow victim to rub or keep eyes closed.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Wash clothing before reuse.

Hazards Identification

Inhalation

Causes respiratory tract irritation. Can produce delayed pulmonary edema.

Skin

Causes skin irritation.

Eyes

Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury. Lachrymator. May cause chemical conjunctivitis.

Ingestion

Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 24/25 36/37/38

EC Safety Phrase

S 26 36/37/39 45

UN (DOT)

2810

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Exposure Effects

Effects may be delayed.

Fire Fighting Measures

Flash Point

97

Autoignition

320

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Containers may explode when heated. Extinguishing media: Use agent most appropriate to extinguish fire. Cool containers with flooding quantities of water until well after fire is out. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Potential

Combustible material: may burn but does not ignite readily.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Disposal Code

2

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Incompatibilities

Strong acids, strong bases, strong oxidizing agents.

Decomposition

Hydrogen chloride, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2810

Hazard Class

6.1

Packing Group

I; II; III

HS Code

2918 30 00