Product Identification

Product Name

1H-Indole-2,3-dione

Synonyms

,3-Dihydro-1H-indole-2,3-dione
1H-Indole-2,3-dione
2,3-Indolinedione
Isatic acid lactam
o-Aminobenzoylformic anhydride
Pseudoisatin

CAS

91-56-5

Formula

C8H5NO2

Molecular Weight

147.13

EINECS

202-077-8

RTECS

NL7873000

RTECS Class

Drug; Reproductive Effector

Merck

13,5119

Beilstein/Gmelin

383659

Beilstein Reference

5-21-10-00221

Physical and Chemical Properties

Appearance

Red-orange solid.

Solubility in water

Soluble

Melting Point

198 - 202

Boiling Point

342

Density

1.472 g/cm3

pKa/pKb

10.34 (pKa)

Partition Coefficient

.34

Usage

Production of vat dyes.

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use.

Handling

Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

EC Safety Phrase

S 22 24/25

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Reproductive effects have been reported in animals.

Poison Class

5

Fire Fighting Measures

Flash Point

220

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Reduce airborne dust and prevent scattering by moistening with water. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Disposal Code

3

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents, strong acids and strong bases.

Decomposition

Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and gases, carbon dioxide.

Transport Information

HS Code

2933 79 00