Product Identification

Product Name

(R)-(-)-alpha-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]benzeneacetic acid

Synonyms

(2R)-2-[(4-Ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-phenylacetic acid
Benzeneacetic acid, alpha-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-, (R)-

CAS

63422-71-9

Formula

C15H17N3O5

Molecular Weight

319.31

EINECS

264-133-8

Beilstein/Gmelin

3629459

Beilstein Reference

5-24-05-00287

Physical and Chemical Properties

Appearance

Powder.

Solubility in water

Very soluble

Melting Point

171

pKa/pKb

3.19 (pKa)

Partition Coefficient

-.02

First Aid Measures

Ingestion

Get medical aid. Wash mouth out with water.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container.

Handling

Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.

Hazards Identification

Ingestion

May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.

Inhalation

Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May cause cardiovascular disturbances, hearing abnormalities, central nervous system depression, muscle weakness, and possible death due to respiratory failure.

Skin

Causes skin irritation. Exposure may cause severe skin burns (2nd and 3rd degree burns).

Eyes

Causes eye irritation.

Exposure Controls/Personal Protection

Personal Protection

Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability

No data.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.