Product Identification

Product Name

2-Methyl-N-(4-nitro-3-[trifluoromethyl]phenyl)propanamide

Synonyms

2-Methyl-N-(4-nitro-3-[trifluoromethyl]phenyl)propanamide
4'-Nitro-3'-trifluoromethylisobutyranilide
N-(Isopropylcarbonyl)-4-nitro-3-trifluoromethylaniline
Niftholide

CAS

13311-84-7

Formula

C11H11F3N2O3

Molecular Weight

276.22000000000003

EINECS

236-341-9

RTECS

UG5700000

RTECS Class

Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Hormone

Merck

12,4242

Beilstein/Gmelin

2157663

Beilstein Reference

6-12

Physical and Chemical Properties

Solubility in water

Insoluble

Melting Point

110 - 111

Boiling Point

400

Vapor Pressure

1E-6 (25 C)

pKa/pKb

13.12 (pKa)

Heat Of Vaporization

65.1 kJ/mol

Usage

Non-steroidal anti-androgen.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.

Exposure Effects

Harmful. Possible risk of harm to the unborn child. Harmful by inhalation, in contact with skin and if swallowed. Target organ(s): Male reproductive system. Possible carcinogen. Calif. Prop. 65 reproductive hazard.

Fire Fighting Measures

Flash Point

196

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen fluoride.

Hazards Identification

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

20/21/22 63

EC Safety Phrase

22 36