Product Identification

Product Name

Lithium 2-methylpropan-2-olate

Synonyms

1,2,3,4,5,6-Hexachlorocyclohexane (mixed isomers)
BCH
Cyclohexane, 1,2,3,4,5,6-hexachloro-
HCH
Kwell
Lindane

CAS

608-73-1

Formula

C6H6Cl6

Molecular Weight

290.82

EINECS

210-168-9

RTECS

GV3150000

RTECS Class

Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Human Data

Beilstein/Gmelin

1907331

Beilstein Reference

2-05-00-00011

Physical and Chemical Properties

Appearance

White to yellow powder or flakes. Musty odor.

Solubility in water

Insoluble

Melting Point

113

Density

1.87 g/cm3 (20 C)

Usage

Control of leafhoppers, stem borers, etc, in lowland rice. Kotol liq seed treatment for reduction of wireworm damage in winter & spring sown cereals. Lindocol for control of pests of cereals, sugar beets & oilseed rape. Former use.

Vapor Density

1.85

Refractive Index

1.52299 (124 C)

First Aid Measures

Ingestion

Seek medical assistance.

Inhalation

Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.

Skin

Remove all exposed clothing and jewelry taking necessary precautions to prevent secondary exposure to health care providers. Irrigate exposed areas promptly with copious amounts of water for at least 30 minutes. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Remove contaminated clothing and jewelry. Wash the skin, including hair and nails, vigorously; do repeated soap washings. Discard contaminated clothing. Carefully observe patient for development of clinical signs and symptoms, and administer treatment as described in dermal exposure where appropriate.

Handling and Storage

Storage

Storage location should be close to laboratory where it is to be used, so that only small amounts need to be transported. Carcinogens should be kept in only one section of storage area, explosion-proof refrigerator or freezer as required. The area should be appropriately labeled. An inventory should be kept showing the quantity of carcinogen and date it was acquired. Facilities for dispensing should be contiguous to storage area.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Effects of contact or inhalation may be delayed.

Skin

Extensive contact may result in dermatitis, irritation, and local hypersensitivity.

Eyes

Lindane can irritate the eyes, nose, and throat.

Ingestion

Nausea, vomiting, diarrhea, hypersalivation, and pancreatitis may occur following ingestion.

UN (DOT)

2761

Exposure Controls/Personal Protection

Personal Protection

Dispensers of liquid detergent should be available. In the laboratory, gloves and protective clothing should always be worn but should not be assumed to provide full protection. Carefully fitted masks or respirators may be necessary when working with particulates or gases, and disposable plastic aprons might provide additional protection. Protective clothing should be of distinctive color, as a reminder not to be worn outside the laboratory.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Exposure Effects

Elevated body temperature and respiratory depression may occur with prolonged seizures. Abnormally low blood pressure may occur with severe poisoning. Central nervous system excitation, agitation, nervousness, tremor, seizures, sensory disturbances, and peripheral neuropathy may occur. Lindane did not have reproductive effects in a 3-generation rat study. It has not been teratogenic in animals. It disturbed the estrus cycle and reduced fertility in female rats. It has been detected in human breast milk. It produced degenerative changes in the testes of rats.

Exposure limit(s)

TLV (as gamma-isomer): ppm; 0.5 mg/m3 (skin) (ACGIH 1991-1992).

Poison Class

3

Fire Fighting Measures

Fire Fighting

Use method most appropriate to fight surrounding fire.

Fire Potential

Not flammable.

Accidental Release Measures

Small spills/leaks

Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.

Stability and Reactivity

Incompatibilities

Incompatible with strong oxidizing and reducing agents Incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Stability

Stable to light, heat, air, carbon dioxide and strong acids.

Decomposition

When heated to decomposition it emits highly toxic fumes of phosgene and hydrogen chloride.

Combustion Products

Toxic gases are generated when solid is heated or when soln burns.

Transport Information

UN Number

2761

Hazard Class

6.1

Packing Group

I; II; III