Product Identification

Product Name

1-[2-(Ethylsulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole

Synonyms

1-(2-(Ethylsulfonyl)ethyl)-2-methyl-5-nitroimidazole
Ethyl [2-(2-methyl-5-nitroimidazol-1-yl)ethyl] sulfone

CAS

19387-91-8

Formula

C8H13N3O4S

Molecular Weight

247.28

EINECS

243-014-4

RTECS

NI6255000

RTECS Class

Drug; Mutagen; Reproductive Effector

Merck

12,9588

Beilstein/Gmelin

618182

Beilstein Reference

5-23-05-00067

Physical and Chemical Properties

Solubility in water

Soluble

Vapor Pressure

1E-10 (25 C)

pKa/pKb

11.66 (pKb)

Heat Of Vaporization

77.3 kJ/mol

Usage

Used to treat protozoal infections, such as amebiasis, giardiasis, and trichomoniasis.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Inhalation

Harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation. Harmful if absorbed through skin.

Eyes

May cause eye irritation.

Ingestion

Harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

20/21/22 40

EC Safety Phrase

26 36

Exposure Controls/Personal Protection

Personal Protection

Compatible chemical-resistant gloves. Chemical safety goggles.

Respirators

Government approved respirator.

Exposure Effects

Harmful. Harmful by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. Possible carcinogen. Possible mutagen.

Fire Fighting Measures

Flash Point

273

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Thermal decomposition may produce carbon monoxide, carbon dioxide, and nitrogen oxides.