Product Identification

Product Name

2-Isocyanatoethyl methacrylate

Synonyms

2-(Methacryloyloxy)ethyl isocyanate
2-Isocyanatoethyl 2-methylprop-2-enoate
2-Isocyanatoethyl methacrylate
2-Propenoic acid, 2-methyl-, 2-isocyanatoethyl ester
Isocyanic acid, 2-hydroxyethyl ester methacrylate (ester)
Methacrylic acid, 2-isocyanatoethyl ester

CAS

30674-80-7

Formula

C7H9NO3

Molecular Weight

155.16999999999999

EINECS

250-284-7

RTECS

OZ4950000

RTECS Class

Reproductive Effector

Beilstein/Gmelin

1768533

Beilstein Reference

4-04-00-01555

Physical and Chemical Properties

Solubility in water

Insoluble

Boiling Point

219

Vapor Pressure

0.12 (25 C)

Partition Coefficient

2.27

Heat Of Vaporization

45.5 kJ/mol

Refractive Index

1.4496 (20 C)

First Aid Measures

Ingestion

Due to the irritant nature of isocyanates, vomiting is not advised. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Monitor patient for respiratory distress. If a cough or difficulty in breathing develops, evaluate for respiratory tract irritation, bronchitis and pneumonia. Allergic reaction - sensitized individuals should be cautioned to avoid further exposure, as serious allergic reactions may result.

Inhalation

Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.

Skin

Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Ingestion

Inhalation of vapor or aerosol may produce vomiting and abdominal pain. Epigastric and substernal pain may be secondary to the paroxysmal or persistent cough associated with inhalation.

Inhalation

Burning or irritation of the nose and throat, cough, laryngitis, chest pain, and asthmatic syndrome (chemical bronchitis with severe bronchospasm) sensation of oppression or constriction of the chest, bronchitis, emphysema and cor pulmonale may occur.

Skin

Irritation and inflammation are common with isocyanates. Isocyanates may burn the skin.

Eyes

See Inhalation.

Hazards

Vapors form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff.

UN (DOT)

3080

Exposure Controls/Personal Protection

Personal Protection

Wear appropriate protective gloves, clothing and goggles.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Fire Fighting Measures

Flash Point

93

Fire Fighting

(Non-Specific -- Isocyanates and Solutions, n.o.s. (Flammable, Poisonous)) Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Wear positive pressure breathing apparatus and special protective clothing. Move container from fire area if you can do it without risk. Cool containers that are exposed to flames with water from the side until well after fire is out. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material.(Non-Specific -- Isocyanates and solutions, n.o.s. (Flammable, Poisonous)) Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog, or foam.

Fire Potential

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.

Accidental Release Measures

Small spills/leaks

(Non-Specific -- Isocyanates and Solutions, n.o.s. (Flammable, Poisonous)) Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Ventilate closed spaces before entering them. Shut off ignition sources; no flares, smoking or flames in hazard area. Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors. Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal. Small dry spills: with clean shovel place material into clean, dry container and cover; move containers from spill area. Large spills: dike far ahead of spill for later disposal.

Stability and Reactivity

Incompatibilities

Incompatible with many classes of compounds, reacting exothermically to release toxic gases Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat.

Stability

No data.

Combustion Products

Fire will produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

3080

Hazard Class

6.1

Packing Group

II