Product Identification

Product Name

2-Amino-9-beta-D-ribofuranosyl-9H-purine-6-(1H)-one hydrate

Synonyms

2(3H)-Imino-9-beta-D-ribofuranosyl-9H-purin-6(1H)-one
Guanine riboside
Guanine, 9-beta-D-ribofuranosyl
Ribofuranoside, guanine-9, beta-D
Vernine

CAS

118-00-3

Formula

C10H13N5O5

Molecular Weight

283.24

EINECS

204-227-8

RTECS

MF8750000

RTECS Class

Mutagen; Reproductive Effector

Merck

13,4582

Beilstein/Gmelin

625911

Beilstein Reference

5-26-18-00084

Physical and Chemical Properties

Appearance

Very slightly beige solid.

Solubility in water

Very soluble

Melting Point

248

Density

1.597 g/cm3

pKa/pKb

9.03 (pKa)

Usage

A purine nucleoside composed of guanine and ribose.

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water. Get medical aid if irritation or symptoms occur.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. No special precautions indicated.

Handling

Wash thoroughly after handling. Wash hands before eating. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

May cause irritation of the digestive tract. Low hazard for usual industrial handling. The toxicological properties of this substance have not been fully investigated.

Inhalation

May cause respiratory tract irritation. Low hazard for usual industrial handling. The toxicological properties of this substance have not been fully investigated.

Skin

May cause skin irritation. The toxicological properties of this material have not been fully investigated.

Eyes

May cause eye irritation. The toxicological properties of this material have not been fully investigated.

EC Safety Phrase

S 22 24/25

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Transport Information

HS Code

2934 99 90