Product Identification

Product Name

1-Amino-2,4-dibromoanthraquinone

Synonyms

1-Amino-2,4-dibromoanthracene-9,10-dione
2,4-Dibromo-1-anthraquinonylamine

CAS

81-49-2

Formula

C14H7Br2NO2

Molecular Weight

381.02

EINECS

201-354-0

RTECS

CB5500000

RTECS Class

Mutagen; Primary Irritant

Beilstein/Gmelin

1993373

Beilstein Reference

4-14-00-00444

Physical and Chemical Properties

Appearance

Odorless red powder.

Melting Point

235

Boiling Point

468

Partition Coefficient

3.27

Usage

Aminoanthraquinones are key products for essentially all classes of anthraquinone dyes. Aminoanthraquinones.

First Aid Measures

Ingestion

DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician.

Inhalation

IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.

Skin

IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

Eyes

First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Dyspnea is mentioned as a sign of severe poisoning.

Skin

Some anthraquinones have been shown to be sensitizers. Finger clubbing has been reported with abuse of senna. The condition is reversible with discontinuation of the drug. Dithranol may cause a burning sensation, especially on perilesional skin.

Ingestion

Nausea, vomiting, abdominal pain, and especially diarrhea may be seen with both therapeutic doses and overdose.

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter.

Exposure Effects

Muscular seizures are a rare sign of severe intoxication. Dizziness is occasionally seen in severe intoxications. CNS depression was seen in animals tested with injections of emodin. Analgesia was also noted with injection. These effects have not been noted in human overdose.

Fire Fighting Measures

Fire Fighting

Fires involving this chemical can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used.

Fire Potential

This chemical is probably combustible.

Accidental Release Measures

Small spills/leaks

If you spill this chemical, you should dampen the solid spill material with 5% acetic acid, then transfer the dampened material to a suitable container. Use absorbent paper dampened with 5% acetic acid to pick up any remaining material. Your contaminated clothing and the absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with 5% acetic acid followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Stability and Reactivity

Incompatibilities

Incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

Stability

No data.