Product Identification

Product Name

2,6-Dihydroxyisonicotinic acid

Synonyms

2,6-Dihydroxy-4-carboxypyridine
2,6-Dihydroxyisonicotinic acid
2-Hydroxy-6-oxo-1H-pyridine-4-carboxylic acid
4-Pyridinecarboxylic acid, 1,2-dihydro-6-hydroxy-2-oxo-
Isonicotinic acid, 1,2-dihydro-6-hydroxy-2-oxo
Isonicotinic acid, 2,6-dihydroxy

CAS

99-11-6

Formula

C6H5NO4

Molecular Weight

155.11000000000001

EINECS

202-731-2

RTECS

NS1400000

RTECS Class

Other

Merck

13,2349

Beilstein/Gmelin

383736

Beilstein Reference

5-22-07-00024

Physical and Chemical Properties

Appearance

Beige slightly brown.

Solubility in water

Very soluble

Melting Point

> 330

Density

1 g/cm3

pKa/pKb

2.14 (pKa)

Partition Coefficient

.91

First Aid Measures

Ingestion

Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Keep container closed when not in use.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Hazards Identification

Ingestion

Causes gastrointestinal irritation with nausea, vomiting and diarrhea.

Inhalation

May cause allergic respiratory reaction. May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema.

Skin

Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.

Eyes

Causes eye irritation.

EC Risk Phrase

R 36/37/38

EC Safety Phrase

S 26 36

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Poison Class

4

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Transport Information

HS Code

2933 39 99