Acetone(67-64-1)
Product Identification
Product Name
Acetone
Synonyms
2-Propanone
Dimethyl ketone
Ketone propane
Propanone
CAS
67-64-1
Formula
C3H6O
Molecular Weight
58.08
EINECS
200-662-2
RTECS
AL3150000
RTECS Class
Tumorigen; Mutagen; Reproductive Effector; Human Data; Primary Irritant
Merck
13,67
Beilstein/Gmelin
635680
Beilstein Reference
4-01-00-03180
EC Index Number
606-001-00-8
EC Class
Highly flammable; Irritant; Repeated exposure may cause skin dryness or cracking; Vapours may cause drowsiness and dizziness
Physical and Chemical Properties
Appearance
Clear, colorless, volatile liquid with a mildly pungent, characteristic sweet, slight aromatic, fruity odor.
Solubility in water
Miscible
Melting Point
-95.4
Boiling Point
56.2
Vapor Pressure
186 (20 C)
Density
0.792 g/cm3 (20 C)
pKa/pKb
20 (pKa)
Partition Coefficient
-.24
Heat Of Vaporization
31.9 kJ/mol
Heat Of Combustion
-1791 kJ/mol
Usage
Solvent for fats, oils, waxes, resins, rubber, plastics, lacquers, varnishes, rubber cements. Laboratory reagent.
Saturation Concentration
24% (20 C) (calculated)
Vapor Density
2
Odor threshold
13 ppm
Refractive Index
1.3591 (20 C)
First Aid Measures
Ingestion
Aspiration hazard. If swallowed, vomiting may occur spontaneously, but DO NOT INDUCE. If vomiting occurs, keep head below hips to prevent aspiration into lungs If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
Storage
Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No Smoking areas. Use non-sparking type tools and equipment, including explosion proof ventilation. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Hazards Identification
Inhalation
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause liver and kidney damage. May cause motor incoordination and speech abnormalities.
Skin
Exposure may cause irritation characterized by redness, dryness, and inflammation.
Eyes
Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury.
Ingestion
May cause irritation of the digestive tract. May cause central nervous system depression, kidney damage, and liver damage. Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. May cause liver and kidney damage. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. May polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
EC Risk Phrase
R 11 36 66 67
EC Safety Phrase
S 9 16 26
UN (DOT)
1090
Exposure Controls/Personal Protection
Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A half-face organic vapor respirator may be worn for up to ten times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece organic vapor respirator may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator.
Exposure Effects
Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation may cause effects similar to those of acute inhalation. Use of alcoholic beverages enhances toxic effects. Exposure may increase the toxic potential of chlorinated hydrocarbons, such as chloroform, trichloroethane.
Exposure limit(s)
TLV: 750 ppm; 1780 mg/m3 (ACGIH 1993-1993). OSHA PEL: TWA 1000 ppm (2400 mg/m3) NIOSH REL: TWA 250 ppm (590 mg/m3) NIOSH IDLH: 2500 ppm LEL
Poison Class
5
Fire Fighting Measures
Flash Point
-20
Autoignition
465
Fire Fighting
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use alcohol foam, dry chemical or carbon dioxide.
Upper exp. limit
12.8
Lower exp. limit
2.5
Fire Potential
Extremely flammable liquid and vapors. The vapors may cause flash fires.
Accidental Release Measures
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Wear appropriate protective clothing to minimize contact with skin. Remove all sources of ignition. Provide ventilation. A vapor suppressing foam may be used to reduce vapors. Water spray may reduce vapor but may not prevent ignition in closed spaces. Clean up residual material by washing area with a 2-5% solution of soda ash.
Stability and Reactivity
Disposal Code
1
Incompatibilities
Concentrated nitric and sulfuric acid mixtures, oxidizing materials, chloroform, alkalis, chlorine compounds, acids, potassium t-butoxide.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Combustion Products
Fire may produce irritating, corrosive and/or toxic gases.