Product Identification

Product Name

Oxatomide

Synonyms

1-(3-(4-(Diphenylmethyl)-1-piperazinyl)propyl)-1,3-dihydro-2H-benzimidazol-2-one
1-(3-(4-(Diphenylmethyl)-1-piperazinyl)propyl)-2-benzimidazolinone
KW-4354
Oxatimide
Oxatomida

CAS

60607-34-3

Formula

C27H30N4O

Molecular Weight

426.56

EINECS

262-320-9

RTECS

DE2276000

RTECS Class

Drug; Reproductive Effector

Merck

12,7058

Beilstein/Gmelin

4724760

Beilstein Reference

6-24

Physical and Chemical Properties

Appearance

White powder.

Solubility in water

Insoluble

Melting Point

153 - 155

pKa/pKb

6.87 (pKb)

Usage

A histamine h1-receptor antagonist. May be useful in managing asthma.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Inhalation

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.

Skin

May cause skin irritation.

Eyes

May cause eye irritation.

Ingestion

Harmful if swallowed.

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

22

Exposure Controls/Personal Protection

Personal Protection

Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves.

Respirators

Government approved respirator.

Exposure Effects

Harmful. Harmful if swallowed.

Fire Fighting Measures

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Incompatibilities

Oxidizing agents, Strong acids.

Stability

Stable at normal temperatures and pressures.

Decomposition

Carbon monoxide, Carbon dioxide, Nitrogen oxides.