Product Identification

Product Name

1-Hydroxy-2-methoxybenzene

Synonyms

2-Methoxyphenol
Anastil
Guaiacol
Guaiastil
Guaicol
o-Guaiacol

CAS

90-05-1

Formula

C7H8O2

Molecular Weight

124.14

EINECS

201-964-7

RTECS

SL7525000

RTECS Class

Mutagen; Human Data; Primary Irritant

Merck

13,4568

Beilstein/Gmelin

508112

Beilstein Reference

4-06-00-05563

EC Index Number

604-031-00-6

EC Class

Harmful; Irritant

Physical and Chemical Properties

Appearance

Colorless to faintly yellowish liquid or white or slightly yellow crystalline mass, darkens on exposure to air or light, characteristic sweet, slightly phenolic odor.

Solubility in water

Slightly soluble

Melting Point

28 - 32

Boiling Point

205

Vapor Pressure

0.18 (25 C)

Density

1.1534 g/cm3 (0 C)

pKa/pKb

9.97 (pKa)

Partition Coefficient

1.32

Heat Of Vaporization

45.9 kJ/mol

Usage

Local anesthetic agent.

Saturation Concentration

197 ppm (0.02%) at 20 C (calculated)

Vapor Density

4.3

Refractive Index

1.5429 (20 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Keep away from sources of ignition. Store in a cool place in the original container and protect from sunlight. Keep under a nitrogen blanket. Store protected from light and air.

Handling

Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with skin and eyes. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light. Store protected from air. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.

Hazards Identification

Inhalation

Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.

Skin

Causes skin irritation.

Eyes

Causes severe eye irritation.

Ingestion

Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause systemic toxicity with acidosis. May be harmful if swallowed.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 22 36/38

EC Safety Phrase

S 26

UN (DOT)

2430

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause fetal effects.

Poison Class

3

Fire Fighting Measures

Flash Point

82

Autoignition

750

Fire Fighting

Fires involving this material should be controlled using a dry chemical, carbon dioxide or Halon extinguisher.

Upper exp. limit

9.6

Lower exp. limit

1.3

Fire Potential

This chemical is combustible.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Provide ventilation.

Stability and Reactivity

Disposal Code

1

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Incompatibilities

Strong oxidizing agents, strong bases, acid chlorides, and acid anhydrides. Darkens upon exposure to light or air, and may decompose.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2430

Hazard Class

8

Packing Group

I; II; III

HS Code

2909 50 10