Product Identification

Product Name

Etodolac

Synonyms

1,3,4,9-Tetrahydro-1,8-diethylpyrano(3,4-b)indole-1-acetic acid
1,8-Diethyl-1,3,4,9-tetrahydropyrano(3,4-b)indole-1-acetic acid
AY-24236
Etodolic acid
Pyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1,8-diethyl-
Ultradol

CAS

41340-25-4

Formula

C17H21NO3

Molecular Weight

287.36

RTECS

UQ0360000

Merck

12,3920

Physical and Chemical Properties

Solubility in water

Slightly soluble

Melting Point

145 - 148

Boiling Point

508

Vapor Pressure

3.9E-11 (25 C)

Density

1.193 g/cm3 (20 C)

pKa/pKb

4.31 (pKa)

Partition Coefficient

3.59

Heat Of Vaporization

81.8 kJ/mol

Usage

Non-steroidal anti-inflammatory drug (nsaid) - of the arylalkanoic acids sub-group - effective in treating pain and inflammation in the body.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician.

Inhalation

If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Store at 2 - 8 C.

Exposure Controls/Personal Protection

Personal Protection

Chemical resistant gloves, safety goggles.

Respirators

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.

Exposure Effects

Toxic by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. Possible teratogen. Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals. Gastrointestinal disturbances. Exposure can cause: Nausea, dizziness, and headache.

Fire Fighting Measures

Fire Fighting

EXTINGUISHING MEDIA Suitable: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Protective Equipment: Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Decomposition

Carbon monoxide, carbon dioxide, and nitrogen oxides.

Combustion Products

Emits toxic fumes under fire conditions.

Hazards Identification

EC Risk Phrase

R: 23/24/25 40

EC Safety Phrase

S: 22 36 45