Product Identification

Product Name

1,1,1,3,3,3-Hexafluoro-2-propanol

Synonyms

1,1,1,3,3,3-Hexafluoro-2-hydroxypropane
1,1,1,3,3,3-Hexafluoroisopropyl alcohol
2,2,2-Trifluoro-1-(trifluoromethyl)ethanol
2-Propanol, 1,1,1,3,3,3-hexafluoro-
Bis(trifluoromethyl)methanol
Hexafluoroisopropyl alcohol

CAS

920-66-1

Formula

C3H2F6O

Molecular Weight

168.04

EINECS

213-059-4

RTECS

UB6450000

RTECS Class

Other

Beilstein/Gmelin

3624201

EC Class

harmful, corrosive

Physical and Chemical Properties

Appearance

A light colored liquid.

Solubility in water

Insoluble

Melting Point

-96

Boiling Point

59.1

Vapor Pressure

158 (25 C)

Density

1.492 g/cm3

pKa/pKb

9.75 (pKa)

Partition Coefficient

1.91

Heat Of Vaporization

59.0 kJ/mol

Vapor Density

5.8

Refractive Index

1.27 (20 C)

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a cool, dry place. Store in a tightly closed container.

Handling

Wash thoroughly after handling. Avoid contact with skin and eyes. Avoid ingestion and inhalation. Use only in a chemical fume hood.

Hazards Identification

Inhalation

Causes respiratory tract irritation. May cause effects similar to those described for ingestion.

Skin

Prolonged and/or repeated contact may cause defatting of the skin and dermatitis. May cause irritation with pain and stinging, especially if the skin is abraded.

Eyes

Causes eye irritation. May cause eye injury.

Ingestion

May cause central nervous system depression, kidney damage, and liver damage. Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor, and coma. May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 20/22 34 41

EC Safety Phrase

S 26 36/37/39 45

UN (DOT)

3265

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause liver and kidney damage.

Fire Fighting Measures

Flash Point

-2

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Substance is noncombustible. Extinguishing media: Use extinguishing media most appropriate for the surrounding fire.

Fire Potential

This chemical is probably combustible.

Accidental Release Measures

Small spills/leaks

Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.

Stability and Reactivity

Disposal Code

2

Stability

Has not been fully evaluated.

Incompatibilities

Strong acids, acid chlorides, oxidizing agents, aluminium, zinc, strong bases.

Decomposition

Carbon monoxide, carbon dioxide, hydrogen fluoride.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

3265

Hazard Class

8

Packing Group

I; II; III

HS Code

2905 59 10