Product Identification

Product Name

2,5-Di(tert-amyl)hydroquinone

Synonyms

2,5-Bis(1,1-dimethylpropyl)-1,4-benzenediol
2,5-Bis(1,1-dimethylpropyl)hydroquinone
2,5-Bis(2-methylbutan-2-yl)benzene-1,4-diol
2,5-di-T-Amylhydroquinone
2,5-di-tert-Amylhydroquinone
2,5-di-tert-Pentylhydroquinone
3,3-Tetramethyleneglutaric anhydride
8-Oxaspiro[4.5]decane-7,9-dione

CAS

5662-95-3

CAS

79-74-3

Formula

C16H26O2

Formula

C9H12O3

Molecular Weight

250.38

Molecular Weight

168.19

EINECS

201-222-2

EINECS

227-116-6

RTECS

MX6300000

RTECS Class

Reproductive Effector

Merck

12,3359

Beilstein/Gmelin

2214556

Beilstein/Gmelin

383703

Beilstein Reference

5-17-11-00080

Beilstein Reference

3-06-00-04748

Physical and Chemical Properties

Appearance

Crystals.

Appearance

White crystals.

Solubility in water

Slightly soluble

Solubility in water

Soluble

Melting Point

185

Melting Point

68

Boiling Point

323

Boiling Point

349

Vapor Pressure

0.0003 (25 C)

Density

1.05 g/cm3 (25 C)

Density

1.28 g/cm3

Partition Coefficient

5.5

Partition Coefficient

.6

Heat Of Vaporization

56.5 kJ/mol

Usage

Antioxidant for uncured rubber & for unsaturated resins & oils, food packaging, polymerization inhibitor.

First Aid Measures

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Ingestion

Seek medical assistance.

Inhalation

Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Inhalation

Move victim to fresh air. Apply artificial respiration if victim is not breathing. Administer oxygen if breathing is difficult.

Inhalation

Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Can produce delayed pulmonary edema.

Skin

Causes skin irritation.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Skin

Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Eyes

Causes eye irritation. May cause chemical conjunctivitis.

Handling and Storage

Storage

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation

Ingestion has caused dyspnea, anoxia, and respiratory failure. Quinone has caused asphyxia and pulmonary damage.

Skin

May cause burns.

Eyes

See Skin.

Ingestion

Vomiting and gi tract irritation have been seen.

UN (DOT)

1325

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Personal Protection

Wear appropriate protective gloves, clothing and goggles.

Respirators

Wear positive pressure self-contained breathing apparatus (SCBA).

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Dizziness, headache and delirium have been reported with hydroquinone exposure. Quinone has cause paralysis of the medullary centers and coma. Both quinone and hydroquinone may cause seizures. In rat studies, maternal toxic effects from exposure to hydroquinone included changes in the ovaries, fallopian tubes, and menstrual cycle. Post-implantation mortality was also observed in rat studies. <br>Observed paternal toxic effects from exposure to hydroquinone included changes in the testes, epididymis, sperm duct, prostate, seminal vesicle, Cowper's gland, accessory glands, and male fertility index. <br>Exposure to hydroquinone produced skeletal malformations in chickens and ocular and skeletal malformations in rabbits.

Exposure Effects

Effects may be delayed.

Poison Class

3

Fire Fighting Measures

Flash Point

155

Fire Fighting

Small Fires: Dry chemical, carbon dioxide, sand, earth, water spray or regular foam. Large Fires: Water spray, fog or regular foam.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.

Fire Potential

Flammable/combustible material. May be ignited by friction, heat, sparks or flames.

Accidental Release Measures

Small spills/leaks

Make no contact with the spilled material. ELIMINATE all ignition sources and ground all equipment. With clean shovel place material into clean, dry container and cover loosely; move containers from spill area.

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability

No data.

Incompatibilities

Oxidizing agents.

Stability

Stable under normal temperatures and pressures.

Decomposition

Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire may produce irritating and/or toxic gases.

Transport Information

UN Number

1325

Hazard Class

4.1

Packing Group

II; III