Product Identification

Product Name

1-(Aminomethyl)cyclohexaneacetic acid

Synonyms

1-(Aminomethyl)cyclohexaneacetic acid
2-[1-(Aminomethyl)cyclohexyl]acetic acid
Neurontin

CAS

60142-96-3

Formula

C9H17NO2

Molecular Weight

171.24

EINECS

262-076-3

RTECS

GU6496000

RTECS Class

Drug

Merck

12,4343

Beilstein/Gmelin

2359739

Beilstein Reference

6-14

Physical and Chemical Properties

Appearance

Off-white powder.

Solubility in water

Very soluble

Melting Point

165 - 152

Boiling Point

314

Vapor Pressure

0.0001 (25 C)

Density

1.257 g/cm3

pKa/pKb

4.72 (pKa)

Heat Of Vaporization

61.1 kJ/mol

Usage

Anticonvulsant with unknown mechanism of action. Exhibits antinociceptive, anxiolytic, neuroprotective and anti-epileptic effects.

First Aid Measures

Ingestion

If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.

Inhalation

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.

Skin

In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.

Eyes

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage

Keep tightly closed.

Hazards Identification

Skin

Causes skin irritation. Multiple Routes: May be harmful by inhalation, ingestion, or skin absorption. Vapor or mist is irritating to the eyes, mucous

Hazards

Emits toxic fumes under fire conditions.

EC Risk Phrase

61 36/37/38

EC Safety Phrase

53 22 26 36/37/39 45

Exposure Controls/Personal Protection

Personal Protection

Wear self-contained breathing apparatus, rubber boots, and heavy rubber gloves. Wear disposable coveralls and discard them after use.

Respirators

Government approved respirator.

Exposure Effects

Toxic. May cause harm to the unborn child. Irritating to eyes, respiratory system and skin. Target organ(s): Nerves. Pancreas.

Fire Fighting Measures

Flash Point

144

Fire Fighting

Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability

Stable at normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Carbon monoxide, Carbon dioxide.