Product Identification

Product Name

TOPO

Synonyms

1-Dioctylphosphoryloctane
Catechins
Cyanex 921
Fresh Shiraimatsu FS 500M
Gallotannic acid
Gallotannin
Glycerite
Hostarex PX 324
TOPO
Tri-n-octylphosphine oxide
Vitanil B

CAS

1401-55-4

CAS

78-50-2

Formula

C24H51OP

Formula

C76H52O46

Molecular Weight

386.65

Molecular Weight

1701.22

EINECS

201-121-3

EINECS

215-753-2

RTECS

SZ1662500

RTECS

WW5075000

RTECS Class

Tumorigen; Mutagen; Reproductive Effector; Natural Product

RTECS Class

Primary Irritant

Merck

12,9221

Beilstein/Gmelin

1796648

Beilstein/Gmelin

8191228

Beilstein Reference

4-04-00-03466

Physical and Chemical Properties

Appearance

Light yellow to tan solid with a faint odor. Gallic acid derivatives found in nutgalls, bark and other plant parts, especially oak bark.

Appearance

White powder.

Solubility in water

Soluble

Solubility in water

Insoluble

Melting Point

218-219

Melting Point

50 - 52

Boiling Point

409

Vapor Pressure

2E-6 (25 C)

Density

>1 g/cm3 (20 C) (solid)

Density

0.88 g/cm3

Partition Coefficient

9.4

Heat Of Vaporization

Heat Of Vaporization

63.5

Heat Of Combustion

-38385 kJ/mol

Usage

Mordant in dyeing, manufacture ink, sizing paper & silk, printing fabrics, tanning, as coagulant in rubber mfr, with gelatin & albumin for manufacture of imitation horn & tortoise shell, clarifying beer or wine, in photography, manufacture gallic acid & pyrogallol, as reagent in analytical chemistry.

First Aid Measures

Ingestion

Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid if irritation or symptoms occur.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver damage.

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Inhalation

Dust is irritating to the respiratory tract.

Skin

May cause skin irritation. May be absorbed through the skin in harmful amounts.

Skin

Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water.

Skin

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

May cause eye irritation. May result in corneal injury.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator (approx 4 C).

Storage

Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed. Store protected from light.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale.

Hazards Identification

Inhalation

Causes respiratory tract irritation. Can produce delayed pulmonary edema.

Skin

Causes skin irritation.

Eyes

Causes eye irritation. May cause chemical conjunctivitis.

Ingestion

May cause gastrointestinal irritation with nausea, vomiting and diarrhea.

Hazards

Contact with metals may evolve flammable hydrogen gas.

EC Risk Phrase

R 34 50/53

EC Risk Phrase

R 40

EC Safety Phrase

S 22 36/37

EC Safety Phrase

S 26 36/37/39 45 60 61

UN (DOT)

1759

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

Chronic ingestion may cause liver damage.

Exposure Effects

Effects may be delayed.

Poison Class

4

Fire Fighting Measures

Flash Point

260

Autoignition

527

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. Extinguishing media: Use water spray to cool fire-exposed containers. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.

Fire Potential

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.

Fire Potential

Slightly. Requires preheating. Slight hazard.

Accidental Release Measures

Small spills/leaks

Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

1

Incompatibilities

Oxidizing agents.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents; strong bases.

Decomposition

Phosphine, carbon monoxide, oxides of phosphorus, irritating and toxic fumes and gases, carbon dioxide.

Decomposition

Carbon monoxide, carbon dioxide, acrid smoke and fumes.

Combustion Products

Decomposes at 210 to carbon dioxide and pyrogallol, which can form irritating vapors.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

1759

Hazard Class

8

Packing Group

I; II; III

HS Code

2931 00 95

HS Code

3201 90 90