Product Identification

Product Name

2-Chloro-N,N-dimethylaniline

Synonyms

o-Chloro-N,N-dimethylaniline

CAS

698-01-1

Formula

C8H10ClN

Molecular Weight

155.62

Beilstein/Gmelin

2205740

Beilstein Reference

4-12-00-01116

Physical and Chemical Properties

Solubility in water

Insoluble

Boiling Point

206 - 208

Vapor Pressure

0.23 (25 C)

Density

1.1067 g/cm3 (20 C)

pKa/pKb

9.60 (pKb)

Heat Of Vaporization

44.4 kJ/mol

Refractive Index

1.5472 (20 C)

First Aid Measures

Ingestion

Administer charcoal as a slurry (240 mL water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents, 25 to 50 g in children (1 to 12 years), and 1 g/kg in infants less than 1 year old Consider gastroc ;avage after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Protect airway by placement in Trendelenburg and left lateral decubitus position or by endotracheal intubation. Control any seizures first.

Inhalation

Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, for respiratory tract irritation bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids.

Skin

Skin should be thoroughly washed with soap and water. Contaminated clothing and shoes should be discarded Seek medical attention. Administer 100 percent humidified supplemental oxygen with assisted ventilation as required. Treat for methemoglobinemia and sequelae. Signs and symptoms of methemoglobinemia may be delayed.

Eyes

Irrigate exposed eyes with copious amounts of room temperature water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Hazards Identification

Ingestion

Nausea and vomiting may occur. Metabolic acidosis may develop secondary to tissue hypoxia.

Inhalation

Dyspnea and tachypnea may occur. CNS effects include headache, dizziness, altered mental status, confusion, lethargy progressing to coma seizures and syncope; these occur secondary to CNS hypoxia, usually with levels > 20 percent.

Skin

Central cyanosis unresponsive to oxygen therapy is classic.

Eyes

Causes severe irritation.

Fire Fighting Measures

Flash Point

74