Product Identification

Product Name

2-Aminoisovaleric acid

Synonyms

(2S)-2-Amino-3-methylbutanoic acid
(S)-2-Amino-3-methylbutyric acid
L-2-Amino-3-methylbutyric acid
L-2-Aminoisovaleric acid

CAS

72-18-4

Formula

C5H11NO2

Molecular Weight

117.15

EINECS

200-773-6

RTECS

YV9361000

RTECS Class

Mutagen

Merck

12,10046

Beilstein/Gmelin

1721136

Beilstein Reference

4-04-00-02659

Physical and Chemical Properties

Appearance

White powder.

Solubility in water

88.5 g/L

Melting Point

86

Boiling Point

217

Vapor Pressure

0.063 (25 C)

Density

1.284 g/cm3

pKa/pKb

2.37 (pKa)

Partition Coefficient

-.01

Heat Of Combustion

-2925 kJ/mol

Usage

One of 20 proteogenic amino acids.

First Aid Measures

Ingestion

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid if irritation or symptoms occur.

Inhalation

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.

Skin

Get medical aid if irritation develops or persists. Wash clothing before reuse. Flush skin with plenty of soap and water.

Eyes

Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. May form flammable dust-air mixtures. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation

The toxicological properties of this substance have not been fully investigated.

Skin

Low hazard for usual industrial handling.

Eyes

No information regarding eye irritation and other potential effects was found. Contact may cause transient eye irritation.

Ingestion

The toxicological properties of this substance have not been fully investigated.

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

The toxological properties of this substance have not been fully investigated.

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. Substance is noncombustible. Extinguishing media: Use water spray, dry chemical, or carbon dioxide.

Accidental Release Measures

Small spills/leaks

Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. Clean up residual material by washing area with a 2-5% solution of soda ash.

Stability and Reactivity

Stability

Stable under normal temperatures and pressures.

Incompatibilities

Strong oxidizing agents.

Decomposition

Nitrogen oxides, carbon monoxide, carbon dioxide.

Transport Information

HS Code

2922 49 95