Product Identification

Product Name

6',12'-Dimethoxy-2,2'-dimethyl-6,7-(methylenebis(oxy))-oxyacanthan

Synonyms

(+)-Cepharanthine
6',12'-Dimethoxy-2,2'-dimethyl-6,7-(methylenebis(oxy))oxyacanthan
Cepharanthin
Cepharantin
O-Methylcepharanoline
Oxyacanthan, 6',12'-dimethoxy-2,2'-dimethyl-6,7-(methylenebis(oxy))-

CAS

481-49-2

Formula

C37H38N2O6

Molecular Weight

606.72

RTECS

FK0527000

Merck

12,2031

Beilstein/Gmelin

75231

Beilstein Reference

4-27-00-09061

Physical and Chemical Properties

Appearance

Yellow powder.

Solubility in water

Insoluble

Melting Point

140 - 145

Density

1.227 g/cm3 (20 C)

pKa/pKb

6.25 (pKb)

Partition Coefficient

5.23

Usage

Stimulates recovery of immunologic function in lymphatic system afte administration of antineoplastic agents or x-irradiation.

Handling and Storage

Storage

Store cool and dry in sealed containers.

Hazards Identification

Inhalation

Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention.

Skin

Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention.

Eyes

Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice.

Ingestion

If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice.

Exposure Controls/Personal Protection

Personal Protection

Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves.

Fire Fighting Measures

Fire Fighting

Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pick-up complete.

Stability and Reactivity

Combustion Products

Emits toxic fumes under fire conditions.