Product Identification

Product Name

2,4-Difluoro-alpha,alpha1-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol

Synonyms

1H-1,2,4-Triazole-1-ethanol, alpha-(2,4-difluorophenyl)-alpha-(1H-1,2,4-triazol-1-ylmethyl)
2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)-2-propanol
alpha-(2,4-Difluorophenyl)-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol
Diflucan
UK-49858

CAS

86386-73-4

Formula

C13H12F2N6O

Molecular Weight

306.27

RTECS

XZ4810000

Merck

12,4158

Physical and Chemical Properties

Appearance

White, crystalline powder.

Solubility in water

Sparingly soluble

Melting Point

138

Boiling Point

580

Vapor Pressure

2.8E-14 (25 C)

Density

1.49 g/cm3 (20 C)

pKa/pKb

11.01 (pKa)

Partition Coefficient

.5

Heat Of Vaporization

91.2 kJ/mol

Usage

Used in the treatment and prevention of superficial and systemic fungal infections.

Handling and Storage

Storage

Store in original container in a cool dark place.

Hazards Identification

Inhalation

Remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention.

Skin

Immediately wash skin with soap and copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention.

Eyes

Immediately flush eyes with copious amounts of water for at least 15 minutes. Seek medical advice.

Ingestion

If swallowed, wash out mouth with water, provided person is conscious. Seek medical advice.

Exposure Controls/Personal Protection

Personal Protection

Wear self-contained breathing apparatus, rubber boots & heavy rubber gloves.

Fire Fighting Measures

Fire Fighting

Extinguish with carbon dioxide, dry chemical powder or appropriate foam. Water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with the skin and eyes.

Accidental Release Measures

Small spills/leaks

Sweep-up/absorb in suitable material, place in a container and hold for disposal. Avoid raising dust. Ventilate area and wash spill site after pickup is complete.

Stability and Reactivity

Combustion Products

Emits toxic fumes under fire conditions.