Product Identification

Product Name

4-Chloro-2-nitroaniline

Synonyms

4-Chloro-2-nitrobenzenamine

CAS

89-63-4

Formula

C6H5ClN2O2

Molecular Weight

172.57

EINECS

201-925-4

RTECS

BX1575000

RTECS Class

Mutagen

Beilstein/Gmelin

512436

Beilstein Reference

4-12-00-01669

EC Index Number

610-006-00-0

EC Class

very toxic, dangerous for the environment

Physical and Chemical Properties

Appearance

Orange crystalline powder.

Solubility in water

Insoluble

Melting Point

116 - 119

Vapor Pressure

.0004

Partition Coefficient

2.64

Usage

Dye and pigment intermediate.

Saturation Concentration

0.5 ppm at 25 C (calculated)

First Aid Measures

Ingestion

Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.

Inhalation

Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.

Skin

Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.

Eyes

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Handling and Storage

Storage

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Handling

Wash thoroughly after handling. Minimize dust generation and accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Take precautionary measures against static discharges. Keep container tightly closed. Avoid ingestion and inhalation. Use only in a chemical fume hood.

Hazards Identification

Inhalation

May cause respiratory tract irritation. May cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea, and death. May cause liver and kidney damage. May cause cardiac abnormalities. Inhalation at high concentrations may cause CNS depression and asphixiation.

Skin

May cause skin irritation. Absorption into the body may cause cyanosis. Causes redness and pain.

Eyes

May cause eye irritation. Causes redness and pain.

Ingestion

May be fatal if swallowed. May cause irritation of the digestive tract. May cause liver and kidney damage. May cause cardiac disturbances. May cause methemoglobinemia, cyanosis, convulsions, and death. May cause headache. May cause nausea and vomiting. May cause central nervous system depression.

Hazards

When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.

EC Risk Phrase

R 26/27/28 33 51/53

EC Safety Phrase

S 28 36/37 45 61

UN (DOT)

2237

Exposure Controls/Personal Protection

Personal Protection

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.

Respirators

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Exposure Effects

May cause liver and kidney damage. May cause methemoglobinemia, which is characterized by chocolate-brown colored blood, headache, weakness, dizziness, breath shortness, cyanosis, rapid heart rate, unconsciousness and possible death. Effects may be delayed.

Fire Fighting Measures

Flash Point

191

Autoignition

530

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Containers may explode when heated. Runoff from fire control or dilution water may cause pollution. Extinguishing media: For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.

Fire Potential

This compound is probably combustible.

Accidental Release Measures

Small spills/leaks

Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code

9

Incompatibilities

Oxidizing agents, strong bases.

Stability

Stable at room temperature in closed containers under normal storage and handling conditions.

Decomposition

Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Combustion Products

Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number

2237

Hazard Class

6.1

Packing Group

III

HS Code

2921 42 10