Product Identification

Product Name

1-(2-Chlorophenyl)-2-thiourea

Synonyms

(2-Chlorophenyl)thiourea
(o-Chlorophenyl)thiourea
1-(2-Chlorophenyl)thiourea
N-(2-Chlorophenyl)thiourea

CAS

5344-82-1

Formula

C7H7ClN2S

Molecular Weight

186.67

EINECS

226-291-6

RTECS

YS7100000

RTECS Class

Agricultural Chemical and Pesticide

Beilstein/Gmelin

776946

Beilstein Reference

3-12-00-01296

Physical and Chemical Properties

Appearance

Needles or plates.

Solubility in water

Slightly Soluble

Melting Point

147

Boiling Point

304

Partition Coefficient

2.03

Usage

2-Chlorophenylthiourea is not manufactured or used as an end-product industrially in the usa.

First Aid Measures

Ingestion

Do not induce emesis. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.

Inhalation

Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.

Skin

Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.

Eyes

Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Handling and Storage

Storage

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Handling

All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Ingestion

See inhalation.

Inhalation

High oral toxicity.

Skin

See inhalation.

Eyes

See inhalation

Hazards

When heated to decomposition it emits very toxic fumes of chlorides, nitrogen oxides, and sulfur oxides.

EC Risk Phrase

R 28

EC Safety Phrase

S 22 28 36/37 45

UN (DOT)

2811

Exposure Controls/Personal Protection

Personal Protection

Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.

Respirators

Use NIOSH/MSHA approved respirator appropriate for exposure of concern.

Poison Class

2

Fire Fighting Measures

Fire Fighting

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks

Do not touch spilled material; stop leak if you can do it without risk. Small spills: take up with sand or other noncombustible absorbent material and place into containers for later disposal. Small dry spills: with clean shovel place material into clean, dry container and cover; move containers from spill area. Large spills: dike far ahead of spill for later disposal.

Stability and Reactivity

Stability

No data.

Incompatibilities

Strong oxidizing agents.

Transport Information

UN Number

2811